Lateral elbow tendinopathy is a common condition, especially in athletes and manual workers. Its etiology remains poorly understood but it is likely multifactorial. No consensus exists as to what are the most effective methods to treat the symptoms associated with lateral elbow tendinopathy. The data suggest that joint mobilizations can help in the treatment of patients: the techniques most investigated are mobilization with movement, Mill’s manipulation and regional mobilization techniques directed to the cervical and thoracic spine. There is evidence that joint mobilizations have a positive effect on both pain and/or pain-free grip in lateral elbow tendinopathy management.