Carpal tunnel syndrome is a condition characterized by compression of the median nerve in its passage through the carpal tunnel: it is the most frequent neuropathy of the upper limb. Among the most studied conservative treatments are the use of night-time splints with the wrist in resting position, injections of cortisone medication, manual therapy, and neurodynamic exercises. In recent years, the latter in particular have become the focus of numerous studies – the patient is required to perform an active treatment which has the potential effect of central desensitization. The article presents three neuro-tendon gliding exercises which produce a gliding movement of the nerve and tendons with respect to the surrounding tissues. These are combined movements that associate the shortening of the neuro-tendon at one point with simultaneous relaxation and elongation at the other.